Researchers in South Korea have identified and characterized an anti-bacterial peptide (small protein) in leech saliva. Using current technological tools and computing, S. Dinesh Kumar and colleagues at the Korea Basic Science Institute described their search, discovery, and characterization of these antibacterial molecules called Hirunipins in the journal “Advance Science”. Not only did they document activity against antibiotic-resistant bacteria and biofilm, such as Acinetobacter, but they also recorded images of the mechanisms by which these small molecules kill the bacteria. To read the study, go to https://advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202409803